Renal calcium handling after rapamycin conversion in chronic allograft dysfunction
نویسندگان
چکیده
منابع مشابه
Chronic renal allograft dysfunction.
The major causes of renal transplant loss are death from vascular, malignant or infectious disease, and loss of the allograft from chronic renal dysfunction associated with the development of graft fibrosis and glomerulosclerosis. Chronic allograft nephropathy (CAN) is the histologic description of the fibrosis, vascular and glomerular damage occurring in renal allografts. Clinical programs rel...
متن کاملConversion from cyclosporine to sirolimus in chronic renal allograft dysfunction: a 4-year prospective study.
OBJECTIVES The long-term use of cyclosporine always contributes to chronic renal allograft dysfunction. Converting from cyclosporine to sirolimus and reducing cyclosporine dosage under high mycophenolate mofetil levels are 2 common therapies. Their efficacy and safety have not been compared in Chinese patients. MATERIALS AND METHODS In this prospective, open label, randomized study, 51 kidney...
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tient’s baseline anticoagulant therapy contributed to the unusually slow progression of vision loss. A few reports propose beneficial effects of anticoagulation and antiplatelet therapy in GCA-related vision loss. Buono et al reported improvement in acuity and posterior ciliary artery blood flow with the addition of heparin sodium therapy in a patient with progressive visual loss despite cortic...
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BACKGROUND We tested the strategy of mTOR inhibitors with calcineurin inhibitor minimization in renal transplant recipients with known chronic allograft dysfunction. METHODS In this open-label, single-arm study, renal transplant patients were recruited after biopsy-confirmed chronic allograft dysfunction in the absence of acute rejection episode within 2 months, with proteinuria <0.8 g/day, a...
متن کاملChronic renal allograft dysfunction: risk factors, immunology and prevention.
INTRODUCTION Kidney transplantation is the treatment of choice for patients with end-stage renal disease. Despite great progress in surgical aspects and immunosupression therapy, long-term graft survival has not been consistent. Chronic allograft dysfunction (CAD) remains a major cause of late grafts failure. REVIEW CAD is a generic term of all causes of chronic renal allograft dysfunction as...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2006
ISSN: 0934-0874,1432-2277
DOI: 10.1111/j.1432-2277.2005.00251.x